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A Case of Congenital Megakaryoblastic Leukemia Accompanied by Down Syndrome Which was Diagnosed by Autopsy Findings.

Journal of the Korean Pediatric Society 1989;32(2):262-269.
Published online February 28, 1989.
A Case of Congenital Megakaryoblastic Leukemia Accompanied by Down Syndrome Which was Diagnosed by Autopsy Findings.
Il Kyung Kim1, Dong Beom lee1, Jung Sik Min1, Chang Hee Choi1, Je Geun Chi2
1Department of Pediatric, Seoul Adrentist Hospital, Seoul, Korea
2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea
부검 소견으로 진단된 Down 증후군을 동반한 선천성 급성 거핵아구성 백혈병 1례
김일경1, 이동범1, 민정식1, 최창희1, 지제근2
1서울위생병원 소아과
2서울대학교 의과대학 소아병리학교실
Received: 10 May 1988   • Accepted: 25 July 1988
Abstract
Many cases of acute megakaryonlastic leukemia have been reported in childhood or adults, but congenital form or the cases occuring in neonatal period is very rare throughout the world. In Korea only one case was reported previously by Chung et al in 1987. The authors experienced a case of congenital megakaryoblastic leukemia accompanied by Down' s syndrome, which was confirmed by autopsy and positive reaction tl anti-factor V III monoclonal antibody. We report this case with a review of literature.
Key Words: Congenital Megakaryoblastic Leukemia, Down’s syndrome


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