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A Case of Spindle Cell Thymoma with Spinal Cord Compression.

Journal of the Korean Pediatric Society 1988;31(9):1237-1242.
Published online September 30, 1988.
A Case of Spindle Cell Thymoma with Spinal Cord Compression.
Ki Hyeok Lee1, Dong Joo Nah1, Jong In Byun1, Sang Min Seong1, Kyung Tai Whang1, Eun Deok Chang2, Young Hee Jee2
1Department of Pediatrics, Catholic University Medical College, Seoul, Korea
2Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea
척수압박 증상을 보인 흉선종 1례
이기혁1, 나동주1, 변종인1, 성상민1, 황경태1, 장은덕2, 지영희2
1가톨릭의과대학 소아과학교실
2가톨릭의과대학 임상병리학교실
Received: 1 February 1988   • Accepted: 1 April 1988
Abstract
We experienced a case who presented symptoms of spinal cord compression in association with posterior mediastinal thymoma. A 2-year old female patient was admitted to the hospital for evaluation of gait difficulty and motor weakness of legs which aggravated during two weeks prior to admission. General physical, mental status examination and cranial nerve functions were within normal limits. Diffuse moderate weakness of the lower extremities was noted and the patient had a difficulty to walk. Hyperreflexia of the legs were present, and plantar responses were extensor. Clonus was also elicited. Sensory impairmant of the lower extremities and bladder dysfunction were felt to be present. Chest X-ray and CT scan of the chest showed a large prevertebral mass pushing the mediastinal structures forward and destruction of T8 verebral body. On 6th hospital day, emergency laminectomy of T8~10 vertebrae with removal of tumor mass from extradural space was performed. Light microscopic examination of the tissue revealed a thymoma consisting predominantly of spindle shaped cells with scattered lymphocytic cells. After operation, neurologic abnormalitites found in the lower extremities began to improve and the patients was discharged in satisfactory condition on 18th hospital day.
Key Words: Thymoma, Posterior mediastinal tumor, Spinal cord compression


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