Goiter in Children. |
Young Wan Kim, Duk Hi Kim, Byeung Ju Jeoung |
Department of Pediatrics, Yonsei University, College of Medicine, Seoul, Korea |
소아의 갑상선 종대에 관한 연구 |
김영완, 김덕희, 정병주 |
연세대학교 의과대학 소아과학교실 |
Received: 30 January 1988 • Accepted: 16 March 1988 |
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Abstract |
We studied 197 cases of patients with goiter who visited Department of Pediatrics, Yonsei University
College of Medicine from January 1980 to June 1987. For each patient, serum T4, free T4, T3, TSH,
antithyroid antibody, and antimicrosomal antibody were analyzed, thyroid scan was performed,
and radioiodine uptake was measured.
Following results were obtained:
1) Male to female ratio of 197 cases of goiter was 1:7.5, predominent in female children, meanwhile
in age distribution 100 cases fell into 10 to 12 year old groups, amounting for 50.8%.
2) In functional classification, group of euthyroid state numbered 119 cases(60.4%), whild groups of
hypothyroidism and hyperthyroidism were 52 cases(26.4%) and 26 cases(13.2%) respectively.
3) According to disease entities, in the euthyroid group, 70 cases(58.8%) of chronic lymphocytic
thyroiditis, 35 cases(29.4%) of simple goiter, 8 cases(6.7%) of follicular adenoma, 3 cases(2.5%) of
subacute thyroiditis, 2 cases(1.7%) of acute suppurative thyroiditis, 1 case(0.9%) of papillary
adenocarcinoma were included. In the group of hypothyroidism, chronic lymphocytic thyroiditis
accounted for 41 cases(78.8%) and dyshormonogenesis 11 cases(21.2%). And in the group of
hyperthyroidism, Graves disease were 17 cases (65.4%), chronic lymphocytic thyroiditis 8 cases (30.
8%) and subacute thyroiditis 1 case (3.8%).
4) Etiologically chronic lymphocytic thyroiditis was the most common, amounting to 119 cases. In
addition, there were 35 cases(17.8%) of simple goiter, 17 cases(8.7%) of Graves disease. 11 cases(5.
6%) of dyshormonogenesis, 8 cases(4.0%) of follicular adenoma and others such as subacute
thyroiditis, aucte suppurative thyroiditis, and papillary adenocarcinoma.
5) In cases of chronic lymphocytic thyroiditis, if hypothyroidism had already occured or lowered
thyroid function was detected at the time of diagnosis, there was increased possibility that they
will result in permanent hypothyroidism. |
Key Words:
Goiter, Chronic lymphocytic thyroiditis |
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