| Iron Deficiency Anemia in Childhood and Diagnostic Significance of Serum Ferritin. |
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Dong Hyub Lee, Ki Hong Park, Kyu Chul Choi, Yong Mook Choi |
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Department of Pediatrics, School of Medicine, Kyung Hee University, Seoul, Korea |
| 소아 철결핍성 빈혈과 혈청 Ferritin의 진단적 의의 |
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이동협, 박기홍, 최규철, 최용묵 |
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경희대학교 의과대학 소아과학교실 |
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Received: 7 November 1987 • Accepted: 28 December 1987 |
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| Abstract |
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In order to elucidate clinical and laboratory findings of the iron deficiency anemia(IDA) in
childhood along with diagnostic significance of serum ferritin, 207 patients were analyzed retrospec-
tively, who were hospitalized at Department of Pediatrics, Kyung Hee University Hospital from
January 1981 to December 1986.
The results were as follows;
1) The incidence of IDA in In-Patient was 1.6%.
2) The sex ratio of male to female was 2.4:1.
3) In age distribution, IDA was most common in the group of 7months to 2years of age (74.4%) due
to nutritional problems and was 2nd common in the group of 12 years to 15 years of age (12.1%) due
to chronic blood loss.
4) Comparing with normal control group. IDA revealed microcytic hypochromic anemia (p<0.001)
but reticulocyte and platelet counts were not significantly different (p<0.2, p<0.4).
5) Comparing with other disease group, IDA showed difference in serum ferritin (p< 0.001), TIBC
(p< 0.001), serum iron (p< 0.001) and transferrin saturation (p< 0.025).
6) During oral iron therapy, the hemoglobin level was significantly increased 7〜 13 days after
treatment (p<0.05) and was markedly increased 30 days later (p<0.001).
7) Serum ferritin showed low correlation with other hematological data including MCV, MCH,
MCHC, TIBC, serum iron and transferrin saturation. |
| Key Words:
Iron deficiency anemia, Serum ferritin |
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