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A Case of Chronic Granulomatous Disease.

Journal of the Korean Pediatric Society 1984;27(11):1141-1146.
Published online November 30, 1984.
A Case of Chronic Granulomatous Disease.
C H Park, M R Roh, S C Park, J O Park, D H Lee, S J Lee
Department of Pediatrics, College of Medicine,Soon Chun Hyang University, Seoul, Korea
만성 육아종 질환 1례
박철훈, 노미란, 박상철, 박재옥, 이동환, 이상주
순천향대학 의학부 소아과학교실
Chronic granulomatous disease is characterized by an inability of patients* leukocytes to generate hydrogen peroxide and to kill non-peroxide forming bacteria, such as staphylococci, E. coli and serratiae etc. We experienced a case of chronic granulomatous disease with recurrent pyogenic infection. It was diagnosed by clinical findings and laboratory examinations including NBT test. Clin- ical findings showed persistent diarrhea since birth, recurrent bacterial pneumonia, perianal abscess, skin infection, supraclavicular lymphadenopathy, eczema, osteomyelitis, and anemia. NBT test was 0%. We made a brief review of literature.
Key Words: Chronic granulomatous disease.

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