Journal of the Korean Pediatric Society 1984;27(9):872-876.
Published online September 30, 1984.
Changes of Plasma Inactive Renin in Newborn Infant and Children.
Pyoung Han Hwang1, Woong Kyou Park1, Heon Sook Lee1, Jung Soo Kim1, Kyung Woo Cho2
1Dept, of Pediatrics, Jeonbug National University, Medical School
2Dept, of Physiology, Jeonbug National University, Medical School
신생아 및 소아에 있어서 혈중 Inactive Renin 의 활성도
황평한1, 박웅규1, 이현숙1, 김정수1, 조경우2
1전북대학교 의과대학 소아과학교실
2전북대학교 의과대학 생리학교실
There have been some suggestion that inactive renin may be a kind of precursor renin. There have not yet been however, founded direct evidence for that suggestion. To understand more about the physiological role of the plasma inactive renin, experiments have been done. The results obtained as follows. 1)In the newborn infants plasma renin activity showed highest level up to the age range of 25 years. 2)Trypsin-activatable plasma inactive renin was very high in newborn infant, thereafter the plasma inactive renin activity did not change in the fuuction of aging. 3)The percent of inactive plasma renin over total plasma renin in the children seemed increasing by aging, and the values were different from the adult. These data suggest that the plasma inactive renin may be controlled by different mechanism from the renin system.
Key Words: Inactive renin, Plasma

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