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Four Cases of Gianotti-Crosti Syndrome.

Journal of the Korean Pediatric Society 1984;27(8):820-826.
Published online August 31, 1984.
Four Cases of Gianotti-Crosti Syndrome.
Yong Gab Kwon, Ki Sup Chung, Kir Yong Kim
Department of PediatTics, College of Medicine, Yonsei University
Gianotti-Crosti 증후군 4례
권용갑, 정기섭, 김길영
연세대학교 의과대학 소아과학교실
The Gianotti-Crosti syndrome, papular acrodermatitis of childhood(PAC), is an infrequently recognized disorder with distinctive characteristics. At present hepatitis B virus is thought to be an etiologic gent. The disease is very rare in Korea, in spite of the high frequency of hepatitis B surface antigen(HBsAg) in the general population. It is known that subtype ayw of the HBsAg may influence the pathogenesis of PAC, but subtype analysis of HBsAg in these disclosed adr. Therefore our studies reconfirmed that PAC may in addition be associated with subtype adr of HBsAg. We believe that the lower incidence of PAC in Korea as compared to thd high incidence of PAC in other parts of the world, such as in the Mediterranean area, may be due to the fact that a higher predisposition to PAC is conferred by subtype ayw of HBsAg.
Key Words: Gianotti-Crosti syndrome, Papular acrodermatitis of childhood(PAC), HBsAg, adr

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