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Clinical Study of Urinary Tract Infection associated with Vesicouretral Reflux.

Journal of the Korean Pediatric Society 1984;27(5):467-474.
Published online May 31, 1984.
Clinical Study of Urinary Tract Infection associated with Vesicouretral Reflux.
Kwang Hyun Kim, Tai Jin Park, Woo Gill Lee
Department of Pediatrics Hanyang University, College of Medicine, Seoul Korea
방당뇨관역류를 동반한 요로감염증에 대한 임상적 관찰
김광현, 박태진, 이우길
한양대학교 의과대학 소아과학교실
Vesicoureteral reflux is the problem frequently found among the patients with, urinary tract infection and is the most common cause of the chronic pyelonephritis in children, and renal scarring and renal growth retardation due to reflux and infection is the most important cause of hypertension and renal failure. The authors studied clinically 13 cases with urinary tract infection associated with vesicoureteral reflux who were admitted to Department of Pediatrics Hanyang University Hospital. The results are; 1)There were no difference in age and sex distributions of the 13 cases with, vesicoureteral reflux. 2)In routine CBC such as Hgb, Het, WBC, there were no significant findings with respect to the vesicoureteral reflux. 3)In urinalysis, proteinuria and pyuria was observed in 9 cases respectively, and hematuria and bacteriuria was found in 3 cases respectively. In urine culture, 5 cases showed no bacterial growth and only 8 cases had bacterial growth. Among these 8 cases, E. coli was cultured in 5 cases, which was frequently cultured species. 4)BUN, creatinine, 24 hours urine protein and creatinine clearance were almostly normal and were not related to the degree of the vesicoureteral reflux except one case who had renal agenesis. 5)CRP and LDH isoenzyme studies gave no support for the diagnosis of urinary tract infection associated with vesicoureteral reflux. 6)Of the 13 cases, 20 renal units were found, but there were no difference of incidence about the grade and affected side. 7)Treatment was performed surgically in 9 cases and medically in 4 cases, respectively. Among 9 cases treated surgically, 6 cases were followed-up and showed no reflux in 4 cases. Among 4 cases treated medically only 1 case was followed-up and showed no reflux.
Key Words: Urinary tract infection, Vesicoureteral reflux

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