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Clinical Observation of The Methemoglobinemia in Childrens.

Journal of the Korean Pediatric Society 1982;25(11):1131-1140.
Published online November 30, 1982.
Clinical Observation of The Methemoglobinemia in Childrens.
Hak Hew Shin, Chull Kwon Chung, Myung Hi Shin, Ji Sub Oh
Department of Pediatrics,Wallace Memorial Baptist Hospital Busajt, Korea
Methemoglobin 혈증의 임상적 관찰
신학휴, 정철권, 신명희, 오지섭
부산 왈레스기념 침례회병원 소아과
The clinical records of 28 cases with. Methemoglobinemia who were admitted to the Dept, of pediatrics, WMBH Busan from January 1978 to December 1981 were reviewed. The following results were obtained. 1) Incidence of Methemoglobinemia, was 17.8% among the all drug intoxication and seasonal incidence was peak in spring(50%). 2) The incidence was higher in boys than girls(60.7%), the highest incidence was noted in the age of 1 to 2 years. 3) The commonest causative agents were D.D.S which were 75% of all cases, Followed by Phenacetin(12.1%), Mafenide acetate(6.1%) and Bismuth(3%). 4) The most common presenting symptoms & signs on admisgi on were Cyanosis(100%), the next were irritability(92.9%), vomiting(42.9%), drowsiness(35.7%), abdominal pain(21.4), -tachycardia(17.9%) and dyspnea(7.1 %). 5) The clinical symptoms and signs of D.D.S. intoxication were noted within 5 hours after ingestion in almost all .cases (95%) and those symptoms and signs were disappeared in 4 days :since the recommendation was institated(92.9%). 6) Methemoglobin levels on admission were over 10% in all cases. 7) Methemogobin levels returned to normal rance within 3 to 5 days after treatment
Key Words: Methemoglobinemia, D.D.S.

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