| Five Cases of Hemorrhagic Disease of Infancy. |
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Jung Sook Moon, Eun Hee Koh, Sang Man Shin, Sang Jhoo Lee |
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Department of Pediatrics, Soon Chun Hyang College, Seoul, Korea. |
| 영아기 출혈성 질환 5 례 |
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문정숙, 고은희, 신상만, 이상주 |
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순천향대학 의학부 소아과학교실 |
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| Abstract |
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A hemorrhagic disease due to acquired prothrombin complex deficiency is presented in five infants from 3 weeks to 2 months of age. There are 2 cases of intracranial hemorrhage, 1 case of hemothorax, 2 cases of gastrointestinal bleeding, 1 case of epistaxis and 3 cases of petechia, purpura or bleeding from injection site. After the administration of vitamin K, bleeding ceased and prolonged prothrombin time was corrected promptly. Vitamin K dependent coagulation factor deficiency due to vitamin K deficiency is accounted for the pathogenesis of bleeding. Diarrhea, treatment with antimicrobial agents and a diet low in vitamin K are suggested as etiologic factors acting together. |
| Key Words:
Hemorrhagic disease,infancy,Vitamin K |
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