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HLA Type in Bronchial Asthma and Atopic Dermatitis.

Journal of the Korean Pediatric Society 1982;25(5):460-466.
Published online May 31, 1982.
HLA Type in Bronchial Asthma and Atopic Dermatitis.
Ji Yoon Chung, Myung Sook Kim, Jung Ju Kim, Dong Hak Shin
Department of Pediatrics, Presbyterian Medical Center, College, of Medicine Keimyung University, Daegu, Korea.
氣管枝端息과 Atopic 皮濟炎에 對한 HLA 型의 硏究
鄭智免, 金明被, 金正珠, 申東鶴
啓明大學校 醫科大學 病院 小兒科
Abstract
Since the histocompatibility was discovered, we have studied and determined many HLA types till the last workshop held in Los Angeles, USA, 1980. Nowadays we apply HLA types to organ transplantation, transfusion of blood, identification of paternity, study of ethnology and diagnosis of a specific disease. In the present study, 20 cases of bronchial asthma and 15 atopic dermatitis patients were selected. HLA types, serum IgE values and eosinophil count were analized and the data were compared with that of control group. The results were as follows: 1) Eosinophilia appeared in both bronchial asthma and atopic dermatitis 50% and 20% respectively. 2) The P-Values between the mean of serum IgE of bronchial asthma and control and atopic dermatitis and control were P<0.01 and P<0.05 respectively, which were statistically significant. 3) HLA type shows no statitically significant relationship between control group and bronchial asthma and atopic dermatitis.
Key Words: Bronchial asthma, Atopic dermatitis, HLA type


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