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A Clinical Study on Anaphylactoid Purpura.

Journal of the Korean Pediatric Society 1981;24(12):1185-1192.
Published online December 15, 1981.
A Clinical Study on Anaphylactoid Purpura.
T K Yoon, T H Lee, S M Shin, S J Lee
Department of Pediatrics, Soon Chun Hyang College, School of Medicine, Seoul, Korea
아나필락시스양 자반증의 임상적 고찰
윤태권, 이태훈, 신상만, 이상주
순천향대학 의학부 소아과학 교실
Anaphylactoid purpura is a common disease in childhood and manifests variable clinical features including hepatomegaly. We analyzed 35 children who were admitted and diagnosed as anaphylactoid purpura at Soon Chun Hyang hospital during the periods of 5 years from September, 1975 to August 1980. The results were as follows: 1)It more frequently affected male than female, in the ratio of 1.5: 1 and occurred in about an half of cases at the age of from 6 to 10 years. 2)It predominantly occurred from February to April (62.9%). 3) Twentyfour cases developed, 1-2 weeks after upper respiratory tract infection, 2 cases after typhoid or Japanese B encephalitis vaccination and 2 cases after blunt trauma or severe-physical exercises. No previous history was detectable in 11 cases (31.4%). 4)Main clinical manifestations were skin (100%), gastrointestinal (77.1%), joint (42.9%), and renal (25.7%) involvements. There were 4 cases (11.4%) which showed all the above symptoms. 5)Hepatomegaly was observed in 10 cases (28.6%):it was noted in 34.6% of the patients who admitted within 7 days after onset and noted in 11.1% of the others. So hepatomegaly was thought to be more associated with the early stage of anaphylactoid purpura. Mean duration of hospitalization was 10.3 days in the group with hepatomegaly and was 6.7 days in the group without it, so we were suggested that anaphylactoid purpura with hepatom-egaly had relatively longer hospital course due to it's early manifestation rather than it’s severity. 6) The erythrocyte sedimentation rate over 21mm/hr was noted in 63.0% of the case
Key Words: Anaphylactoid purpura, Hepatomegaly, Vaccination

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