Journal of the Korean Pediatric Society 1981;24(4):329-335.
Published online April 15, 1981.
The Clinical Study on 100 Cases of Congenital Syphillis.
Jheog Hee Hahn, Ok Sung Chung, Mi Seon Lee, Young Shin Kwark, Mi Seon Kim
Department of Pediatrics, Il Sin Womens Hospital, Busan, Korea
선천성 매독환아 100 예의 임상적 비교관찰
한정희, 정옥승, 이미선, 곽영신, 김미선
부산 일신부인병원 소아과
The authors studied 100 cases of congenital syphilis in the newborn treated at II Sin. Women* s Hospital from 1st August 1978 to 31st July 1979. 71 infants were born in the hospital and 29 were admitted from the out patient department. The results were as follows 1.The incidence of congenital syphilis was 1% of live born deliveries. 2. Incidence of prematurity among congenital syphilitic infants delivered at the hospitaL was 17.8% among the group whose mothers were treated during pregnancy, 56% among those whose mothers who did not receive treatment, and 59 社 among congenital syphilitic babies admitted from outpatient department. 3.Clinical minifestations in order of frequency were anemia, hepatomegaly skin lesions, jaundice and bleeding and the incidence was much higher in the untreated compared to the treated group. 4.Bone changes were mainly seen in the untreated group and were mainly seen in th& metaphysis followed by periosteum and diaphysis. 5.The incidence of raised SGOT was also higher in the untreated group. 6.Among 32 infants 9 showed positive VDRL in CSF examination, and this was not related to increase in cell count or protein. 7.Mortality was 3. 5% in the treated group and 27% in the untreated group.
Key Words: Congenital syphilis, Intrauterine infection

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