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Therapeutic Trial with Intravenous Human Sern Globulin and Antibiotics in Several Infections Diseases in Children.

Journal of the Korean Pediatric Society 1980;23(12):1042-1047.
Published online December 15, 1980.
Therapeutic Trial with Intravenous Human Sern Globulin and Antibiotics in Several Infections Diseases in Children.
I J Seol, W G Lee, S J Moon, C M Park
Department of Pediatrics, Hanyang University College of Medicine Seoul, Korea.
小兒期 感染性 疾患에 對한 靜注用 Human Serum Globulin 의 補助的 治療效果에 關한 硏究
薛仁俊, 李愚吉, 文秀之, 朴鍾茂
漢陽大學校 醫科大學 小兒科學敎室
Abstract
We had comparative studies the effect of combined therapy of intravenous human immune serum globulin and antibiotics in the treatment of various infectious diseases from October 1979 to March 1980. The following results were obtained. 1. Total 37 cases including 24 male and 13 female and age distributions were from 1 month to 11 years of age. 2. Intravenous drip infusions were ranging 0.5gm (minimum) to 1.5gm (maximum) in total dose, with lOOmg/kg. 3. Most favorable effects (response) were observed to pertussis, hepatitis, mumps and measles, and less effective for pneumonia, sepsis, typhoid fever, and M.C.L.S. 4. None of the side effects or complications were observed in our study cases. 5. Prophylactic as well as therapeutic use of intravenous immune serum globulin are highly recommended for certain infections such as pertussis, hepatitis, measles, mumps, and bacterial infections combined with antibiotics.


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