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Histiocytic Medullary Reticulosis in childhood Report of Three Cases.

Journal of the Korean Pediatric Society 1980;23(10):833-842.
Published online October 15, 1980.
Histiocytic Medullary Reticulosis in childhood Report of Three Cases.
Kwan Sub Chung1, Kyo Sun Kim1, Do Kwang Yun1, Pyung Kil Kim1, Kir Young Kim1, Byung Soo Kim1, Tae Jung Kwon2, In Jun Chor2
1Deptartment of Pediatirics and Yonsei University, Seoul, Korea.
2Department of pathology, College of Medicine, Yonsei Universty, Seoul, Korea.
조직구성 수성 망상증 3예보고 및 문헌적 고찰
정관섭1, 김교순1, 윤도광1, 김병길1, 김길영1, 김병수1, 권태정2, 최인준2
1연세의대 소아과학 교실
2연세의대 병리학교실
Abstract
Three cases of hisiocytic medullary reticulosis occurring in children aged 6 years, 9 years and 14 years, are described. In all children the diagnosis was based on anemia, granulocytopenia, thrombocytopenia and marked erythrophagocytosis by bone marrow and lymph node atypical histiocytes. They all showed immediate remission with combined chemotherapy of vinblastine and prednisolone, but Case 1 eventually died at 6 months after onset of this rapidly progressive, fatal illness and Case 2, 3 are alive 14 months after onset of their illness.


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