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Late Hemorrhagic Disease of Infancy.

Journal of the Korean Pediatric Society 1980;23(7):572-577.
Published online July 15, 1980.
Late Hemorrhagic Disease of Infancy.
Joong Gon Kim, Young Min Ahn, Hyo Seop Ahn, Yong Choi, Kwang Wook Ko
Dept. of Pediatrics, College of Medicine, Seoul National University, Korea.
Late Hemorrhagic Disease of Infancy (嬰兒期 出血性 疾患) 4例 報告
金重崑, 安永敏, 安孝變, 崔 鏞, 高光昱
서울大學校 醫科大學 小兒科學敎室
Abstract
A hemorrhagic disease due to prothrombin complex deficiency os described in 4 infants from 1 to 11 months of age. This disease is different from the hemorrhagic disease of the newborn. The main differences are that it is found in an older age group and that intracranial hemorrhages are frequent. Rapid clinical and laboratory response after vitamin K therapy are observed. Severe prothrmbin complex deficiency due to vitamin K deficiency is a accounted for the pathogenesis of bleeding. Possible causes of vitaimn K deficiency are reviewed.


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