| Serum C3 Levels in Acute Poststerptococcal Glomerulonephritis. |
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Jun Hee Sul, Chul Lee, Pyung Kil Kim, Duk Jin Yun |
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Department of Pecliatrics, Yonsei University College of Medicine Seoul, Korea. |
| 소아 급성사구체신염에서
혈청 C3치의 변화에 관한 관찰
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설준희, 이 철, 김병길, 윤덕진 |
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연세대학교 의과대학 소아과학교실 |
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| Abstract |
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Acute Poststreptococcal glomerulonephritis is generally stated to be the most common cause of acute nephritis in childhood. The activity of serum complement has been studied in various diseases in an attempt to accumulate evidence of antigen-antibody reaction. In acute poststreptococcal glomerulonephritis, several investigators have reported a decrease in serum complement early in the course of disease. This paper reports on observation of serum C3 levels in 41 cases of poststreptococcal glomerulonephritis which were collected from department of pediatrics, Yonsei University Medical College, from Aug 1978 to March 1979 The results were as follows : 1. The mean value of serum C3 concetration in this group as a whole was lower than in the control group and the difference was statistically significant(p<0.001) 2. The initial reduction of serum C3 concentration did not correlate with the severity of the acute phase of the disease. 3. In those children with acute poststreptococcal glomerulonephritis, Serum C3 concentration returned to normal within 6 weeks. |
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