| A Trend of Serum C3 and C4 levels in Acute Poststreptococcal Glomerulonephirtis. |
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Dong Seok Choi, Young Hun Chung |
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Department of Pediatrics, College of Medicine, Chungnam National University, Dae Jeon, Korea |
| 소아 급성 사구체신염에서 혈청 C3 및
C4치의 의의 |
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최동석, 정용헌 |
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충남대학교 의과대학 소아과학교실 |
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Received: 10 December 1988 • Accepted: 30 December 1988 |
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| Abstract |
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Acute poststreptococcal glomerulonephritis is generally stated to be the most common cause of
acute nephritis in childhood and secondary to an immunologic mechanism.
In acute poststreptococcal glomerulonephritis, there have been several reports on the change of
serum complement levels in the course of disease.
This paper reports on observation of change of serum C3 & C4 levels and its clinical significance
in 41 cases of acute poststreptococcal glomerulonephritis who were admitted in department of
pediatrics, College of Medicine, Chungnam National University, from March 1985 to February 1988.
The results were as follows:
1) Comparing with control group, initial serum C3 levels were reduced in most cases (98%) and
initial serum C4 levels were reduced in 41% (p< 0.001).
2) The initial reduction of serum C3 levels was not correlated with 24hrs urine protein, creatinine
clearance, duration of proteinuria and hematuria
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| Key Words:
Acute poststreptococcal glomerulonephritis, Serum C3 & C4 levels |
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