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Diagnostic Value of Serum Immunoglobulins in Glomerulonephritis.

Journal of the Korean Pediatric Society 1981;24(7):652-658.
Published online July 15, 1981.
Diagnostic Value of Serum Immunoglobulins in Glomerulonephritis.
Pyung Kil Kim, Kyo Sun Kim, Chul Lee, Nan Ae Kim, Jae Seung Lee
Department of Pediatrics, Yonsei university college of medicine, Seoul, Korea.
사구체신염에 있어서 혈청 면역글로불린의 의의
김병길, 김교순, 이철, 김난애, 이재승
연세대학교 의과대학 소아과학교실
Abstract
Serum immunoglobulin concenatrations were measured in 156 patients with various types of glomerulonephritis such as acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. 1) Serum IgG level was above normal mean in acute poststreptococcal glomerulonephritis, and normal range in Henoch-Scholein purpura nephritis. Serum IgG concentrations were significantly reduced in minimal lesion nephrotic syndrome. 2) Serum IgA concentrations were normal limit in minimal lesion nephrotic syndrome. In one-forth of acute poststreptococcal glomerulonephritis and one-half of Henoch-Sch?lein purpura nephritis, serum IgA concentrations were elevated. 3) Serum IgM concentrations were normal in acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. We concluded that serum immunoglobulin concentrations were not useful as an aid in diagnosing glomerulonephritis.
Key Words: Glomerulonephritis, Acute poststreptococcal glomerulonephritis, Minimal lesion nephrotic syndrome, Henoch-Schonlein purpura nephritis


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