| Diagnostic Value of Serum Immunoglobulins in Glomerulonephritis. |
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Pyung Kil Kim, Kyo Sun Kim, Chul Lee, Nan Ae Kim, Jae Seung Lee |
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Department of Pediatrics, Yonsei university college of medicine, Seoul, Korea. |
| 사구체신염에 있어서 혈청 면역글로불린의 의의 |
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김병길, 김교순, 이철, 김난애, 이재승 |
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연세대학교 의과대학 소아과학교실 |
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| Abstract |
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Serum immunoglobulin concenatrations were measured in 156 patients with various types of glomerulonephritis such as acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. 1) Serum IgG level was above normal mean in acute poststreptococcal glomerulonephritis, and normal range in Henoch-Scholein purpura nephritis. Serum IgG concentrations were significantly reduced in minimal lesion nephrotic syndrome. 2) Serum IgA concentrations were normal limit in minimal lesion nephrotic syndrome. In one-forth of acute poststreptococcal glomerulonephritis and one-half of Henoch-Sch?lein purpura nephritis, serum IgA concentrations were elevated. 3) Serum IgM concentrations were normal in acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. We concluded that serum immunoglobulin concentrations were not useful as an aid in diagnosing glomerulonephritis. |
| Key Words:
Glomerulonephritis, Acute poststreptococcal glomerulonephritis, Minimal lesion nephrotic syndrome, Henoch-Schonlein purpura nephritis |
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