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Clinical Study on Tuberculous Meningitis in Infancy and Childhood.

Journal of the Korean Pediatric Society 1978;21(11):753-761.
Published online November 30, 1978.
Clinical Study on Tuberculous Meningitis in Infancy and Childhood.
Jun Hee Sul, Kee Choon Kim, Ki Young Lee, Duk Jin Yun
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
소아의 결핵성 뇌막염에 관한 임상적 고찰
설준희, 김기춘, 이기영, 윤덕진
연세대학교 의과대학 소아과학교실
A clinical study was carried out on 575 cases with tuberculous meningitis who were admitted to the department of pediatrics, Yonsei University College of Medicine during the 18 years from January 1959 to December 1976. The following results were obtained. 1.The age incidence was highest in the age of 2 to 5 and 89.1% were under the age of 8 years. Male to female ratio was 1.5:1 2.The seasonal incidence in order of frequency were spring (30.9%), summer (25.9%), autumn(20.8%) and winter (22.4%). 3. 25% out of the 575 cases had the source of infection infamily members. 4. The tuberculous skin test showed positive reaction in 53.5% 5. The common chief complaints in order of frequency were fever, vomiting, convulsion, unconsciousness and headache. 6. At the time of admission, 80% of 575 cases were diagnosed as meningitis. 7. The major neurologic findings were unconsciousness (34.7%) neck stiffness (86.2%) and positive Kernings sign(62.7%) 8. Chest X-Ray showed normal in 11.6% an miliary tuberculous in 13.7% 9. According to the findings of C.S.F., increased pressure, high protein and low sugar level were associated with poor prognosis. But there were no significant differences on mortality in relation with cell count and chloride level. 10.Mortality rate was 17.5%. Highest mortality was noted in young infants.

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