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A case of transient myeloproliferative disorder in Down's syndrome.

Journal of the Korean Pediatric Society 1991;34(12):1740-1744.
Published online December 31, 1991.
A case of transient myeloproliferative disorder in Down's syndrome.
Dong Uk Kim, Woo Ki Lee, Eung Won Park, Kwang Woo Kim
Department of Pediatrics, Sunrin Hospital, Pohang, Korea
Down 증후군에 동반된 일과성 골수증식장애 1례
김동억, 이우기, 박응원, 김광우
포항선린병원소아과
Received: 9 May 1991   • Accepted: 25 July 1991
Abstract
Transient myeloproliferative disorder has been reported in infants with Down’s syndrome. This disorder is clinically and hematologically indistinguishable from congenital leukemia. In contrast to congenital leukemia, complete clinical and hematological recovery occurs within weeks to months of diagnosis without antileukemic treatment. We experienced a case of Transient myeloproliferative disorder with Down’s syndrome. This 4-day-old female neonate showed jaundice, hepatomegaly, fever, dyspnea, mongoloid face and congenital heart disease (VSD). A brief review of literatrue was made
Key Words: Down's syndrome, transient myeloproliferative disorder


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