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Clinical Studies on Purpuras

Journal of the Korean Pediatric Society 1967;10(3):153-158.
Published online March 31, 1967.
Clinical Studies on Purpuras
Hyo Koon Moon1, Sang Duck Cha1, Doo Uhn Ehm1, Soo Sup Lah2
1Departmemt of Pediatrics, Catholic Medical College
2Department of Internal Medicine,Catholic Medical College
紫斑病의 臨床的 考察
文孝君1, 車相德1, 陰斗銀1, 羅秀燮2
1가톨릭醫大 小兒科學敎室
2가톨릭醫大 內科學敎室
Clinical and hematological examinations were performed on patients manifesting various types of cutaneous hemorrhagic tendencies treated at the Department of Pediatrics and Internal Medicine of Catholic Medical Center over the period January 1962 through July 1964. Materials and Methods Subjects consisted of fity-nine cases and besides the routine physical and laboratory examinations the following hematological tests were performed on each case in order to classify them from etiological point of view: bone marrow examination, bleeding time, coagulation time, recalcificatioa clotting time, platelet count, Rumpel-Leede's test, plasma fibrinogen, prothrombin time, Factor V and Factor Vll-complex determinations, throboplastin, thromboplastin generation test and fibrinolytic activity. Results 1.Majority of patients were under age of 39 and highest incidence was to be seen in one to nineteen years of age group (44.0%) and no significant sex predominance was to be noted. 2.Rashes were predominantly found in the lower extremities and gastrointestinal bleeding, epistaxis, hematuria and vaginal bleeding were the main non-cutaneous hemorrhagic phenomena accompanying purpura. 3.Following were the main disease entities underlying as the cause for the bleeding tendencies in these patients. Anaphylactoid purpuras 21 cases(35.6%) Leukemias 11 cases(18.6%> Thrombocytopenic states (including 3 cases of I.T.P.) 6cases(10.2%) Hemophilias (A-four cases and B-one case) 5cases (8.5%) Korean epidemic hemorrhagic fever 4cases (6.7%>Aplastic anemia 3cases Fibrinolytic purpura 3cases (5.1%) Miscellaneous conditions (Aspidium poisoning etc.) 6cases(10.2%)

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