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Clinical and Hematological Studies of Leukemia in Children

Journal of the Korean Pediatric Society 1975;18(2):104-112.
Published online February 28, 1975.
Clinical and Hematological Studies of Leukemia in Children
C.M. Park, H.T. Kwon, J. J. Yoo
Department of Pediatrics, College of Medicine,Hanyang University
小兒白血病의 血液學的 臨床的 硏究
朴鍾茂, 權會泰, 劉載仲
漢陽大學校 醫科大學 小兒科學敎室
A total of 35 cases of leukemia in children who were admitted at the Hanyang University Hospital during the past two and half years from May 1972 to Oct. 1974 were analysed clinically and hematologically. Following could be summarized; 1.The Incidence of Leukemia was about 5per 1, 000 pediatric inpatient. 2.Common chief complaints in order of frequency were fever (34%), weakness (17%), bleeding tendency (14%), and pallor (14%), 3. Common objective signs were hepatomegaly (66%), splenomegaly (51%), lymphadenopathy(23%), and purpura (petechiae) (17%). 4.Hemogolobin Value below 4 gm% were found in 9 cases (26%), below 6 gm% in 15 cases- (43%),below 8 gm% in 23 cases (66%) where as above 10 gm% in 5 cases (14%). 5. The Leukocyte counts were variable, but tendency of leukocytosis was found in 25 cases (72%), where as leukopenia was found in 25 cases (14%), 6.Platelet counts were decreased in 30 cases (85.7%), marked thrombocytopenia below 10, 000 /mm3 were found in 4 cases (11%), but marked thrombocytosis were noticed in 2 cases (over 1 million and 5 millions). 7. Distribution of the cytological types was as follows: 32 patients with leukemia were acute type, among which Monoblastic, Monomyelogenous, Histiocytic, Lymphoblastic, and Reticulum cell Leukemia in order of frequency. 8. Sex distribution of Leukemia patients was quite different, male patients were more prevalent being male to female ratio 2.4 : 1. 9.Age distribution of Leukemia patients was variable, 0~2 years age group showed the highest morbidity (43%), with 66%, in up to 5 years old age. 10.Reviewing and comparing the reference on the studies of leukemia in children. The distribution of various cytological types were quite different from those of other reported datas.

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