Systemic Cryptococcosis |
S.K. Kim1, K.J Nam1, S.H Shin1, K.J Kim1, D.K Chung2 |
1Department of Pediatrics Presbyterian Medical Center’ Jeon-ju, Cheon-buk, Korea 2Department of Clinical Pathology Presbyterian Medical Center’ Jeon-ju, Cheon-buk, Korea |
Systemic Cryptococcosis |
김석곤1, 남기종1, 신성 희1, 김기준1, 정동규2 |
1전주 예수병원 소아과 2전주 예수병원 임상병리과 |
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Abstract |
Cryptococcal infection is now not so rare a disease in Far East Asia. The7 authors present two
esses of systemic cryptococcosis experienced in our pediatric department. Casel had involvement of
the liver, spleen, kidney, lymph nodes, adrenal glands and brain, and case 11 C.N.S. and liver.
Numerous cryptococcus neofor mans were found in the affected organs and tissues.
The authors discuss incidence, diagnostic problems and drugs. Routine India ink preperation and
repeat of spinal fluid examination were emphasized in the case sof meningitis. In ambiguous cases,
urine, sputum, blcod, bone marrow and stool examination can help identify a fungus infection.
Amphotericin-B is the most effective drug to combat fungal infection up to present. 5-fluorocy-tocine is a new drug, but more evaluation is required because of little experience with it.
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