| Lactic Dehydrogenase Activity in the Serum of Brain Damaged Rabbits |
|
Sang Hyeup Kim1, Kook Choo Rie1, Sung Woo Shin |
1Department of Pediatrics, College of Medicine, Seoul National University
2Department of Pediatrics, Han II Hospital |
| 家兎腦損傷에 依한 血淸 Lactic dehydrogenase 活性度에 關한 硏究 |
|
金相協1, 李國柱1, 申星雨 |
1서울大學校 醫科大學小兒科學敎室
2韓一病院小兒科 |
|
|
|
|
| Abstract |
|
Estimation of the levels of tissue enzymes in the circulating blood has become a useful aid to
diagnosis of cell damage in many organs, but enzyme changes in the blood following brain damage have
been found to be inconstant. In order to clarify it, authors carried out the investigation of changes of serum lactic dehydrogenase in experimentally induced rabbit brain injury.
Following injection of 0.05 ml of 0. 1% AgNO3 solution into the rabbit brain by stereotaxic apparatus,
we examined serum lactic dehydrogenase activity by spectrophotometer.
The following results were obtained. 1. Marked elevation of LDH, above 1000 u/ml of mean value, were observed in caudate nucleus, globus pallidus and midbrain.
2. Moderate elevation of LDH, between 500 u/ml and 1, 000 u/ml were observed in mammillary body, hippocampus, putamen and amygdala.
|
|
PDF Links
Download Citation
