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Total cholesterol level and lactic dehydrogenase activity in cerebrospinal fluid in children

Journal of the Korean Pediatric Society 1965;8(5):23-26.
Published online November 30, 1965.
Total cholesterol level and lactic dehydrogenase activity in cerebrospinal fluid in children
Hak Soo Han, Dae Sung La, He Yung Lee
Dept, of Pediatrics, Chonnam University Medical School
小兒腦脊髓液內 總 Cholesterol 量 및 Lactic Dehydrogenase (L. D.H.) 活性度의 病的動態
韓學洙, 羅大誠, 李義英
全南大學校醫科大學小兒科學敎室
Abstract
Changes in the level of cerebrospinal fluid total cholesterol and lactic dehydrogenase activities in 12 cases of tuberculous meningitis and 27cases of encephalitis Japonica were investigated including 14 cases of healthy children as control. Normal values in the 14 cases were found to be almost similar to those reported by others, thus the total cholesterol being zero mg/dl and the L.D.H. a ctivities 74 units. The 7cases of tuberculous meningitis and 16 cases of encephalitis Japonica in non-comatous state showed slight increase in both total cholesterol level and L. D. H. activity, whereas the other 5 cases of tuberculous meningitis and 11 cases of encephalitis Japonica in comatous state showed markedly increased in both total cholesterol level and L.D.H. activity. The increase in the L.D.H. activites was more pronounced in encephalitis Japonica than in the tuberculous meningitis. The results of this statistical study seem significant in view of the fact that the P value is under 0.01.


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