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Two cases of juvenile pernicious anemia in Korean sisters have been followed for 4 years since 7
years and 4 years of age respectively. The symptoms and signs were pale facies, general malaise, sore
tongue, anorexia, frequent febrile episodes, macrocytic anemia, thrombocytopenia, multilobulated leu-
cocytes with more than 6 lobules and megaloblastic proliferation in bone marrow aspiration. Dramatic
hematological response to the parenteral administration... |