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Original Article
Mutations in Hepatitis B Virus Precore and Core Promotor in Children with Chronic Hepatitis B Infection - Comparison Between Vertical and Non-vertical Transmission -
Jin Kuk Kim, Yeong Hong Park, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 2000;43(6):779-791.   Published online June 15, 2000
Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection. Methods : Sera from 46 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction product of HBV DNA. In this study, the patients were divided...
Hepatitis B Virus Precore and Core Promotor Mutations in Children with Chronic Hepatitis B Infection
Woo Yeong Chung, Jin Kuk Kim, Yeong Hoon Kim, Yeong Hong Park, Chul Ho Kim
Clin Exp Pediatr. 1999;42(10):1392-1402.   Published online October 15, 1999
Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection. Methods : Sera from 31 children with chronic HBV infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA. Results : Twenty-nine adr type were analyzed. The mutations...
Case Report
A Case of Type Ⅱ Ehlers-Danlos Syndrome
Dong Hwan Oh, Jin Kuk Kim, Beuyng Do Nam, Ju Eun Lee, Je Hong Park
Clin Exp Pediatr. 1999;42(2):268-273.   Published online February 15, 1999
Ehlers-Danlos syndrome represents a group of inherited connective tissue disorders characterized by varying degrees of joint laxity, skin fragility and hyperextensibility, and a bleeding tendency. The essential defect is a quantitative deficiency of collagen. At present, 10 clinical forms have been recognized on the basis of extent and severity of the principal features, in combination with other abnormalities and the...
A Case of Septic Pulmonary Embolism in Neonate
Sang Hee Lee, In Hoon Lee, Jin Kuk Kim, Byung Do Nam, Ju Seok Lee, Jae Hong Park
Clin Exp Pediatr. 1998;41(9):1304-1308.   Published online September 15, 1998
Septic pulmonary embolization is an uncommon condition in which the clot or fibrin matrix, contaminated with micro-organisms, lodge in the pulmonary arterial tree, leading to infarction, suppuration and other complications. The septic emboli reach the lung from a variety of sources, including acute suppurative pelvic thrombophlebitis, infective endocarditis involving tricuspid and pulmonary valve, osteomyelitis, suppurative lesions of the neck, infected...
Original Article
An effect of IV methylprednisolone in acute idiopathic thrombocytopenic purpura.
Jin Kuk Kim, Kyeong Hee Hong, Tae Gyu Whang, Soon Yong Lee
Clin Exp Pediatr. 1991;34(9):1240-1245.   Published online September 30, 1991
The major goal in the treatment of acute idiopathic thrombocytopenic purpura (ITP) is to increase the platelet count above the critical level of 20,000/mm3 to avoid intracranial hemorrhage. We have treated eighteen children with acute ITP whose platelet count were below 20,000/mm3 at initial diagnosis. Thirteen of 18 patients (group A) received IV methylprednisolone (IVMP) 10〜20 mg/kg/day for 5 days from the day of...
A case of histiocytic necrotizing lymphadenitis.
Jin Kuk Kim, Jong Bum Shin, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1991;34(4):582-586.   Published online April 30, 1991
We experienced a case of histiocytic necrotizing lymphadenitis in a 10-year old male child with complaints of high fever and painful swelling on right cervical area for 11 days. The diagnosis was based on histopathologic findings of right cervical lymph node, clinical features and laboratory findings. A review of literatures was also presented briefly.