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Original Article
The Effect of Prolonged Treatment in Children with Chronic Hepatitis B with Combination of Alpha-Interferon and Acyclovir
Jeong Ok Hah, Kyoung A Lee
Clin Exp Pediatr. 1993;36(12):1701-1706.   Published online December 15, 1993
This study was conducted to evaluate the effect of prolonged treatment in children with chronic hepatitis B will combination of alpha-interferon and acyclovir. The study population consisited of & patients with chronic hepatitis B who showed histological findings compatible with chronic active hepatitis (4 cases) or chronic persistent hepatitis (3 cases) on liver biopsy and had elevated AST and ALT with...
The Effect of Low-Dosage Alpha-Interferon Therapy in Children with Chronic Active Hepatitis B.
Hee Kyung Kim, Sung Min Choi, Cheol Woo Ko, Kun Soo Lee, Ja Hoon Koo, Doo Hong Ahn
Clin Exp Pediatr. 1990;33(7):915-922.   Published online July 31, 1990
A clinical trial was conducted to determine the effect of low-dosage recombinant a-interferon therapy in children with HBs Ag and HBe Ag positive chronic active hepatitis. Studied patients consist of 7 biopsy-proven children (aged 6.5-11.5 yr). After 16 weeks of therapy, following results were obtained. Out of 7 HBe Ag positive cases, 5 cases (71.4%) were converted to HBe Ag negative state. One of two...
A Clinical and Pathologic Study on Chronic Hepatitis in Infancy and Childhood.
Ki Sub Jung, Chan Ill Park
Clin Exp Pediatr. 1987;30(1):35-44.   Published online January 31, 1987
A clinical and pathologic study was undertaken on 46 cases of chronic hepatitis who had been admitted to Department of Pediatrics, Yonsei University College of Medicine during the period of 6 years from August, 1979 to July, 1985. The results were as follows: 1) Of 46 patients with chronic hepatitis, 40 cases were caused by hepatitis B virus, 3 cases by autoimmunity, and in 3 cases...
Case Report
A Case of Chronic Active Hepatitis with Vertical Transmission.
T H Son, T S Song, H J Park, M J Shin, J G Chi
Clin Exp Pediatr. 1984;27(2):164-169.   Published online February 28, 1984
We experienced a case of Chronic Active Hepatitis with vertical transmission in a 4-year-3-month old boy. Diagnosis of CAH was confirmed by histologic features of liver biopsy. The mode of infection in this case was suspected as vertical transmission by clinical history. His mother had acute hepatitis B in the last trimester of the pregnancy of this boy and had...
A Case of Chronic Active Hepatitis.
H J Park, H K Park, H J Chun, M J Shin, S C Kang
Clin Exp Pediatr. 1981;24(10):991-996.   Published online October 15, 1981
Chronic active hepatitis (CAH) is defined as ongoing inflammation within the liver sustained beyond the expected time of resolution. The etiology of CAH is not completely understood, but hepatitis B infection, drugs such as oxyphenisatin, isoniazid, and alpha-methyldopa, and altered immunity are considered. The most common findings are jaundice, hepatosplenomegaly, elevated serum transaminase activities, hypergammaglobulinemia, and positive "autoimmune" serologic tests,...