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Eleven children with refractory acute leukemia were treated with high dose cytosine arabinoside
(HD Ara-C), given at a dosage of 3 gm/m2 intravenously over about one hour every 12 hours for four
to eight doses. The antileukemic effects were evaluable in nine of the patients, two with ALL, seven
with ANLL. Six of the seven patients with ANLL attained complete remission, while neither... |
