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Enterotoxigenic Escherichia coli (ETEC) cause an acute cholera-like diarrhea in both human and
animals. The disease process involves colonization of the mucosal surfaces of the small intestine
followed by elaboration of ST and/or heat-labile enterotoxin (LT). Intestinal colonization by ETEC
is mediated by specific surface-associated fimbrial or fibrillar antigens including colonization factor
antigens (CFA) I and II.
Isolates of E. coli from 114 children with... |