To evaluate myocardial conductivity to understand cardiac involvement in patients with mitochondrial disease.

We performed retrospective study on fifty-seven nonspecific mitochondrial encephalopathy patients with no clinical cardiac manifestations. The patients were diagnosed with mitochondrial respiratory chain complex defects through biochemical enzyme assays of muscle tissue. We performed standard 12-lead electrocardiography (ECG) on all patients.

ECG abnormalities were observed in 30 patients (52.6%)....