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Original Article
Production, Characterization, and Clinical Application of Perchloric Acid Extract of M. bovis BCG (BCG I)
Kyung Hyo Kim, Dong Soo Kim
Clin Exp Pediatr. 1992;35(8):1059-1065.   Published online August 15, 1992
Tuberculosis has been an important world-wide infectious disease. The prevalence of radiologically active tuberculosis was 1.8% of population in Korea. Probably the most important aspect of the pathogenesis of tuberculosis is the nature and specificity of the response of the immune system to the antigens of tubercle bacilli. Preparation of purified antigens from Mycobacteria with specific antigenic deterninants would improve...