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Purpose : Vigabatrin is a widely used antiepileptic drug that greatly increases whole brain γ- aminobutyric acid(GABA). But little is known about the anticonvulsant effect of vigabatrin on pilocarpine-induced seizures in the immature rats. This study was conducted to determine the effects of vigabatrin on pilocarpine-induced seizures in the immature rats.
Methods : Six to eight day old Sprague-Dawley rats were... |