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Original Article
Prognostic significance of minimal residual disease detected by a simplified flow cytometric assay during remission induction chemotherapy in children with acute lymphoblastic leukemia
Kyung Nam Koh, Meerim Park, Bo Eun Kim, Ho Joon Im, Chan-Jeoung Park, Seongsoo Jang, Hyun Sook Chi, Jong Jin Seo
Clin Exp Pediatr. 2010;53(11):957-964.   Published online November 30, 2010
Purpose

Our study attempted to determine the prognostic significance of minimal residual disease (MRD) detected by a simplified flow cytometric assay during induction chemotherapy in children with B-cell acute lymphoblastic leukemia (B-ALL).

Methods

A total of 98 patients were newly diagnosed with precursor B-ALL from June 2004 to December 2008 at the Asan Medical Center (Seoul, Korea). Of those, 37 were eligible for...

Case Report
Four Cases of The Imported Falciparum Malariain Childre
So Young Lee, Tae Sung Ko, Hyun Sook Chi, Young Seo Park
Clin Exp Pediatr. 1997;40(2):249-253.   Published online February 15, 1997
Malaria is a protozoan disease transmitted by the bite of female Anopheles mosquitoes. Only four species of Plasmodium can infect human, which are P.vivax, P. ovale, P. malariae, and P. falciparum. We experienced four cases of the imported falciparum malaria in children who were admitted due to fever, vomiting, diarrhea, abdominal pain, lethargic state, and/or altered mentality after traveling Kenya and Tanzania without...
Rhinocerebral Mucormycosis : A case Report
Kyuchul Choeh, Hae Jin Choeh, Jung Hae Park, Chong Sung Chung, Won Sil Huh, Hyun Sook Chi
Clin Exp Pediatr. 1992;35(9):1267-1271.   Published online September 15, 1992
We experienced a case of rhinocerebral form of mucormycosis in a 9-year-old male suffered from acute lymphocytic leukemia(FAB L2). On 15th day of induction chemotherapy(Hospital day 23) pain, tenderness and swelling on left maxillary sinus. He expired on Hospital day 47.
Original Article
A Study of Maternal IgG Anti-A, B in ABO Hemolytic Disease of Newborn: Relation between Antibody titer in Mother and Clinical Severity in Neonate.
Chong Woo Bae, yong Mook Choi, Chang Il Ahn, Hyun Sook Chi
Clin Exp Pediatr. 1988;31(8):999-1006.   Published online August 31, 1988
Only IgG anti-A, or Anti-B cross the placenta and are responsible for the occurrence of ABO hemolytic disease of newbom(HDN). We have conducted the role of IgG anti-A or anti-B in mothers to occurrence and severity of the disease with were related to the level of antibodies in pathogenesis of ABO-HDN. This report presents the relation between the degree of bilirubin, hemoglobin concentration in ABO-HDN...