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Case Report
A Month-Old Infant with Chronic Granulomatous Disease Presented as Pulmonary Aspergillosis
SY Bae, JH Jung, KH Kim, YM Hong, HS Koo, JY Seoh, KS Hong, ES Kang, YS Won, JH Yoo
Clin Exp Pediatr. 2000;43(3):444-449.   Published online March 15, 2000
Chronic granulomatous disease(CGD) is an uncommon inherited disorder in which phagocytic cells fails to produce antimicrobial superoxide(O2-) due to NADPH oxidase deficiency. This disease can be easily screened by PMA(phobol myristate acetate)-activated nitroblue tetrazolium(NBT) test. Also the disease has features of chronic pyogenic infection, granuloma formation, anemia, hypergammaglobulinemia, and leukocytosis. Treatment uses antibiotics sensitive to specific organism, surgical drainage...
A Case of Chronic Granulomatous Disease
So Young Lee, Dae Chul Kim, Sung Hee Oh, Hahng Lee, Hyang Eun Sohn, Wha Soon Chung, Young Hyeh Ko, Moon Hyang Park
Clin Exp Pediatr. 1992;35(5):704-712.   Published online May 15, 1992
Chronic granulomatous disease (CGD) is a hereditary disorder of neutrophil with defective killing and digesting of ingested catalase-positive bacteria or fungi in spite of normal phagocytosis. Dissemination of ingested live organisms results in multiple granuloma in reticuloendothelial system and multiple abscesses manifested by recurrent pus-draining suppurative lymphadenopathy, subcutanous abscess, or impetiginous skin rahses, pheumonitis, and hepatosplenomegaly, ultimately resulting in death. Two...
Original Article
The Nitroblue Tetrazoliom Dye Reduction Test in Epidemic Encephalitis Children.
Young Youn Choi, Kong In KWon, Hyung Suk Byun, Kyung Ryong Huh, Chull Sohn
Clin Exp Pediatr. 1981;24(3):221-228.   Published online March 15, 1981
Nitroblue Tetrazolium (NBT) dye can be reduced to water insoluble formazan by peripheral neutrophils during phagocytosis. A study was performed to evaluate the clinical significance of the NBT dye test in epidemic encephalitis children. The results obtained from the NBT dye test in 100 patients with epidemic encephalitis and 14 healthy children were asfollows; 1.The percentage and the absolute number of...
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