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Original Article
Hematology
Effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major: a single-center study
Mahmoud A. El-Hawy, Nagwan Y. Saleh
Clin Exp Pediatr. 2022;65(8):405-409.   Published online June 7, 2022
Question: What is the effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major?
Finding: The dual-energy x-ray absorptiometry scan findings of children with β-thalassemia major and osteoporosis were improved after pamidronate administration.
Meaning: Cyclic pamidronate effectively treated osteoporosis in children with β-thalassemia major.
Endocrinology
The effect of low-dose intravenous bisphosphonate treatment on osteoporosis in children with quadriplegic cerebral palsy
Soon Jeong Moon, Young Min An, Soon Ki Kim, Young Se Kwon, Ji Eun Lee
Clin Exp Pediatr. 2017;60(12):403-407.   Published online December 22, 2017
Purpose

Quadriplegic children with cerebral palsy are more susceptible to osteoporosis because of various risk factors that interfere with bone metabolism. Pamidronate is effective for pediatric osteoporosis, but there are no guidelines for optimal dosage or duration of treatment in quadriplegic children with osteoporosis. We aimed to evaluate the efficacy of low-dose pamidronate treatment in these patients.

Methods

Ten quadriplegic patients on antiepileptic...

Review Article
Pediatric dual-energy X-ray absorptiometry: interpretation and clinical and research application
Jung Sub Lim
Clin Exp Pediatr. 2010;53(3):286-293.   Published online March 15, 2010
Peak bone mass is established predominately during childhood and adolescence. It is an important determinant of future resistance to osteoporosis and fractures to gain bone mass during growth. The issue of low bone density in children and adolescents has recently attracted much attention and the use of pediatric dual-energy X-ray absorptiometry (DXA) is increasing. The process of interpretation of pediatric...
Case Report
A Case of Graves Disease with Kyphosis by Osteoporosis
Yo Won Na, Kee Hyoung Lee, Kee Hwan Yoo, Young Sook Hong, Ju Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2001;44(8):971-975.   Published online August 15, 2001
Graves disease is the most common clinical feature of hyperthyroidism in childhood. Clinical manifestations include emotional lability, hyperactivity, tremor, excessive sweating, exophthalmos and weight loss. In Graves disease, osteoporosis could occur because of a disturbance of mineral homeostasis which rarely develops from reduced calcium absorption of the gastrointestinal tract and increased urinary calcium excretion related to an increased bone resorption....
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