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A Case of Hyperthyroidism Following Primary Hypotyroidism

Journal of the Korean Pediatric Society 1995;38(6):863-866.
Published online June 15, 1995.
A Case of Hyperthyroidism Following Primary Hypotyroidism
Han Sung Cho, Hwang Jae Yoo, Sang Ook Park, Jae Hong Park, Su Young Kim
Department of Pediatrics, Pusan University College of Medicine, Pusan, Korea
갑상선 기능 항진증으로 전환된 원발성 갑상선 기능 저하증 1례
조한산, 유황재, 박상웅, 박재홍, 김수영
부산대학교 의과대학 소아과학교실
A 9-year-old girl presented with primary hypothroidism have been followed by the development of hyperthyroidism. The diagnosis of primary hypothyroidism had been made by clinical manifestation, elavated serum thyroid-stimulating hormone level, antithyroglobulin antibody and antimicrosome antibody. Five and a quarter years later, the diagnosis of hyperthyroidism had been made by clinical maifestation such as enlargemetn of thyroid gland, tahcycardia, increased serum triiodothyronine, free thyroxine levels, radioactive iodine eptake and thyroid stimulating antibody. Now, this patent have been treated by propylthiouracil 100mg/24hours, shwing normal hormonal function of thyroid gland. Conclusively, We must observe it during follow up period that primary hypothroidism caused by autoimmune thyroiditis was not continued, but could progress hyperthyroidism.
Key Words: Primary hypothyroidism, Spontaneous hyperthyroidism

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