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A Case of Neuronal Heterotopia

Journal of the Korean Pediatric Society 1997;40(8):1173-1177.
Published online August 15, 1997.
A Case of Neuronal Heterotopia
Jeong Hae Joo, Eun Joo Seok, Min Jeong Kim, Son Sang Seo
Department of Pediatrics, Il Sin Christian Hospital, Pusan, Korea
뇌량팽대부 무형성증을 동반한 이소성 회백질 1례
주정해, 석은주, 김민정, 서손상
일신기독병원 소아과
Neuronal migrational disorders of the brain represent abnormalities in the formation of the neocortex caused by faulty migration of the subependymal neuroblasts. The neuroblasts normally migrate between the sixth and 15th gestational week and in doing so form the six-layered neocortex. When the migration does not occur in a normal fashion the resultant brain anomalies include lissencephaly, pachygyria, schizencephaly, hemimegalencephaly, heterotopia, and polymicrogyria. Neuronal heterotopia is a collection of nerve cells in abnormal locations as a result of arrest of their radial migration, improper formation, or destruction of the radial glial fiber. We reported a case of neuronal heterotopia with brief review of related literatures.
Key Words: Neuronal heterotopia, Agenesis of corpus callosum, Neuronal migration disorders

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