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Clinical Change of Mycoplasma Pneumonia

Journal of the Korean Pediatric Society 1998;41(3):315-322.
Published online March 15, 1998.
Clinical Change of Mycoplasma Pneumonia
Jae Bum Lee, Kyong Tae Whang, Jeong Hyun Kim, Kyong Og Ko, Ji Hee Cho, Yun Duk Yoo
Department of Pediatrics, Sun Genernal Hospital, Taejeon, Korea
Mycoplasma 폐렴의 임상 양상의 변화
이재범, 황경태, 김정현, 고경옥, 조지희, 유연덕
대전선병원 소아과
Kyong Og Ko, Email: 1
: It was noted some changes of clinical manifestations of mycoplasma pneumonia. we reviewed and compared these changes and saught any clues causes for proper dignosis and treatment.
: We divided patients with mycoplasma pneumonia into two groups, Group 1(from Jan. to Dec. 1996) and Group 2(from Jan. to Dec. 1994), and analyzed clinical, radiologic, and serologic differences.
: Mean age of onset lowered markedly from was 8.34±2.56 years to 6.91±3.28 years(P<0.05). In clinical symptoms, high fever lasted longer and gastrointestinal symptoms were more frequent noted group 1. Serologically, high titers of mycoplasma-specific antibody(>1 : 1280) were more frequently observed in group 1 and correlated with severity of clinical manifestations. In radiologic findings, alveolar consolidation were significantly prominent findings in Group(P < 0.05). The mean period of response to Roxithromycin was not difference between two groups but longer lasting fever(≥3 days) in spite of medication were more prevalent in Group 1(P <0.05), suggesting increased cases of diminished responsiveness to treatment.
: Recently, there was some clinical changes of mycoplasma pneumonia, lowering of onset age, severe clinical symptoms, and more decreased responsiveness to antibiotic treatment. We suggest that it is to neccessary to make some efforts to prevent antibiotics abuse and to decrease the occurrence of resistant strains by introducing of new method for early diagnosis, selective identification of micro-organism and minute sensitivity test for antibiotics.
Key Words: Mycoplasma pneumonia, Clinical change

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