| Comparison between Pathologically and Clinically Diagnosed Group of Acute Postinfectious Glomerulonephritis |
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Chul Hong Kim, Su Yung Kim |
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Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea |
| 생검 및 비생검으로 진단된 급성 감염후 사구체신염의 비교 |
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김철홍, 김수영 |
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부산대학교 의과대학 소아과학교실 |
Correspondence:
Chul Hong Kim, Email: 1
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| Abstract |
Purpose
: Postinfectious acute glomerulonephritis usually needs no renal biopsy. But atypical clinical course and laboratory results indicate a need for renal biopsy. Therefore, to investigate clinicopathological characteristics of postinfectious acute glomerulonephritis, we compared clinical manifestations of biopsy group with those of non-biopsy group.
Methods
: We reviewed the records of clinical and pathological data of 20 cases diagnosed by renal biopsies and compared them with 23 cases only diagnosed clinically.
Result : Male : female ratio was 4.8 : 1 in biopsy group and 1.2 : 1 in non-biopsy group, so the male is more predominent in number in the biopsy group. Hypertension was documented in 52.2% of cases of non-biopsy group, which is significantly high compared to incidence of hypertension (20%) in the biopsy group. Laboratory data showed that serum creatinine, cholesterol, and 24- hour urine protein losses are significantly higher in the biopsy group. In the biopsy group,
tentative diagnosis on admission were acute glomerulonephritis(45.0%), nephrotic syndrome(15.0%), membranoproliferative glomerulonephritis(15.0%), pyelonephritis(10.0%) and so on. Mean time from onset of symptoms to renal biopsy was 29.3¡¾24.1(7-110) days. Fifty percent of the cases showed exudative phase, 25.0% exudative-proliferative phase. In three cases over 7 weeks, two showed proliferative phases and one sclerotic phase.
Conclusion
: Our cases of postinfectious acute glomerulonephritis diagnosed by renal biopsy had a male predominence, and lower incidence of hypertension They also tended to have decrease renal function and more urinary protein loss compared to clinically diagnoses ones without renal biopsy. |
| Key Words:
Postinfectious glomeluronephritis, Renal biopsy |
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