| Measles, Mumps, and Rubella Immunization in Children with Egg Allergies |
|
Seung Yeon Nam, Eun Hee Jung, Jin A Jung, Yong Min Park, Kyoung Hee Jeon, Ju Suk Lee, Gi Young Jang, Kang Mo Ahn, Sang Il Lee |
|
Department of Pediatrics, School of Medicine, Sungkyunkwan University, Seoul, Korea |
| 계란 알레르기가 있는 환아에서의 MMR 예방접종 |
|
남승연, 정은희, 정진아, 박용민, 전경희, 이주석, 장기영, 안강모, 이상일 |
|
성균관대학교 의과대학 소아과학교실 |
Correspondence:
Sang Il Lee, Email: yeon126@unitel.co.kr
|
|
|
|
|
| Abstract |
Purpose
: The safety of MMR(Measles, Mumps, and Rubella) immunization to children with egg
allergies has been debated for decades because the live attenuated virus used in the vaccine is
grown in cultured chick-embryo fibroblasts. Many studies that investigated adverse reactions to
MMR vaccine have been reported abroad, but there has been no report in Korean children. So,
this study is aimed at determining the prevalence of positive reactions to skin test with the
diluted MMR vaccine and the safety of MMR immunization in Korean children with egg allergies.
Methods
: Twenty children who have atopic dermatitis or urticaria associated with egg allergies
in Samsung Medical Center underwent prick and intradermal tests with diluted MMR vaccine.
Then, we administered the vaccine to the children subcutaneously.
Results
: One patient(5.0%) had a positive result on the prick test and five(25.0%) on the intradermal
test. Urticaria was elicited after MMR immunization in two children(10%) who had past
illness of urticaria. One of them had a positive result on the prick and intradermal tests, but the
other had negative results on both tests.
Conclusion
: Although anaphylaxis did not appear in our study, adverse reactions to MMR vaccination
can occur in children with egg allergies, regardless of skin test result to MMR vaccine,
prick or intradermal. Thus, in children with a history of severe systemic allergic reaction to egg,
it is safe to perform MMR vaccination in a tertiary medical center where emergency care can be
taken appropriately. |
| Key Words:
MMR(Measles, Mumps, and Rubella) vaccine, Egg allergy |
|
PDF Links
Download Citation
