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Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome

Korean Journal of Pediatrics 2004;47(7):803-806.
Published online July 15, 2004.
Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome
Ko Un Chun, Soo Yun, Byung Ho Cha, Hae Yong Lee
Department of Pediatrics, Wonju College of Medicine, Yonsei University, Wonju, Korea
Stevens-Johnson 증후군 이후에 발생한 폐색성 세기관지염 1례
전고은, 윤수, 차병호, 이해용
연세대학교 원주의과대학 소아과학교실
Hae Yong Lee, Email: leehy@wonju.yonsei.ac.kr
Bronchiolitis Obliterans(BO) is one of the rare inflammatory lung disease that primarily affects bronchi and bronchioles, followed by partial or complete obstruction. In children, the etiology of BO has been under consideration, but infections and toxic inhalation, connective tissue diseases, lung transplantation, congestive pulmonary edema, etc., may be causes of BO. Even though steroid therapy was reported as an effective treatment, there are few data regarding the epidemiology, pathophysiology, long term prognosis and therapy. Here we describe a 5-year-old boy who presented with intractable wheezing associated with Stevens-Johnson syndrome after Varicella-Zoster virus infection and was diagnosed as BO through chest high-resolution computed tomography.
Key Words: Bronchiolitis obliterans, Stevens-Johnson syndrome, Herpesvirus 3, Human

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