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The relationship between diuresis and pulmonary function in respira- tory distress syndrome of the newborn.

Journal of the Korean Pediatric Society 1991;34(8):1086-1092.
Published online August 31, 1991.
The relationship between diuresis and pulmonary function in respira- tory distress syndrome of the newborn.
Eun Ae Park, Yung Sook Ko, Gyoung Hee Kim
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea
호흡곤란증후군 환아에서의 뇨배설량과 폐기능의 관계
박은애, 고영숙, 김경희
이화대학교 의과대학 소아과학교실
Received: 15 March 1991   • Accepted: 4 April 1991
Abstract
The purpose of this study was to determine the relationship between improvement of pulmonary, function and diuresis in respiratory distress syndrome. This study was based on 24 cases of RDS infants admitted in NICU of Ewha Womans University from January 1988 to December 1990. The results were as follows. 1) Mean birth weight of study cases was 2.11 kg with gestational age between 29〜39 weeks. 2) Maximum FiO2 (inspired oxygen concentration) of mechanical ventilator was between 0.3 to 1. 0 and maximum respiratory rate was between 40~90 breaths per minute and maximum PEEP (peak end expiratory pressure) was 3—9 CmH20. 3) Mean age at onset of diuresis was 27.5 hours of postnatal age with maximum diuresis at 44.2 hours. 4) After diuresis, changes of alveolo-arterial oxygen gradient, inspired oxygen gradient, peak end expiratory pressure and respiratiory rate were statistically significant. On the basis of our observations, we conclude that the increase in urine output precedes the recovery of pulmonary function in infants treated with mechanical ventilation for RDS.
Key Words: RDS (respirator distress syndrome), Diuresis, Pulmonary function


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