Journal of the Korean Pediatric Society 1991;34(2):287-291.
Published online February 28, 1991.
A case of thrombasthenia.
Yong Bae Suh, Eun Kyoung Sohn, Yong Mook Choi, Chang Il Ahn
Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
혈소판 무력증 1례
서용배, 손은경, 최용묵, 안창일
경희대학교 의과대학 소아과학교실
Received: 13 August 1990   • Accepted: 17 October 1990
Abstract
Glanzmann’s thrombasthenia is a congenital disorder of platelet function with missing or abnormal platelet plasma membrane glycoprotein Ilb/IIIa which function as receptors for fibrinogen and other high-molecular-weight adhesive proteins which are important for platelet aggregation. We have experienced a case of thrombasthenia in a 12 month old male whose chief complaints were easy bruising and frequent epistaxis. The beeding time was prolonged in the presence of normal platelet levels and the platelet aggregation test showed lack of aggregation after exposure to ADP, epinephrine and collagen but aggregation response to ristocetin. Platelet adhesion was also decreased. The review of the literature was made briefly.
Key Words: Glanzmann's Thrombasthenia, Platelet aggregation test


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