Journal of the Korean Pediatric Society 1991;34(2):273-280.
Published online February 28, 1991.
Two cases of islet cell hyperplasia with nesidioblastosis.
Myeong Ku Cho1, Kyeong Bae Park1, Gyu Bum Cho1, Dong Hwan Lee1, Sang Jhoo Lee1, D.H Lee2
1Department of Pediatrics, College Medicine, Soon Chun Hyang University, Seoul, Korea
2Department of Clinical Pathology , College Medicine, Soon Chun Hyang University, Seoul, Korea
Nesidioblastosis를 동반한 췌장 소도세포 비후 2례 *
조명구1, 박경배1, 조규범1, 이동환1, 이상주1, 이동화2
1순천향대학교 의과대학 소아과학교실
2순천향대학교 의과대학 임상병리학교실
Received: 13 August 1990   • Accepted: 28 September 1990
Abstract
Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or adenoma. We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was found, but histology revealed islet cell hyperplasia and nesidioblastosis. After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other showed normal glucose value.
Key Words: Islet Cell Hyperplasia, Nesidioblastosis


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