| Diagnostic Significance in Case with Growth Hormone Deficient Dwarfs. |
|
Duk Hi Kim, Mi Jung Park, Yan Kyu Lee |
|
Deptartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea |
| 성장호르몬 결핍성 왜소증의 진단적 의의 |
|
김덕희, 박미정, 이완규 |
|
연세대학교 의과대학 소아과학교실 |
|
Received: 20 August 1990 • Accepted: 14 September 1990 |
|
|
| Abstract |
|
As the scope for treatment with GH widens, it is of interest to evaluate those criteria that are used
conventionally for diagnosis of GH deficiency.
11 patients with hypotha lamic-pituitay lesions and 11 patients with idiopathic GH deficiency
underwent retesting GH secretion with insulin or arginine stimulation test. All 11 parients with
organic GH deficiency remained GH deficient. Of the 11 retested patients with idiopathic GH
deficiency, however, five (45.4%) had peak GH responses of > 10 ng/ml. In 6 patients apparently GH
deficient on these conventional tests of GH secretion, GRF was given intravenously for differentiation
from hypothalamic or pituitary defect. Over than 50% of GH deficient children appeared to have a
defect in hypothalamic secreion.
In summary, organic GH deficiency can be persisted permanently but some of idiopathic GH
deficiency can be changed to normal on retesting GH secretion |
| Key Words:
GH deficiency, Diagnosis of GH deficiency |
|
PDF Links
Download Citation
