A Case of Mucinous Cystadenocarcinoma in a Premenarchal Girl.

Koo, Hong Hoe; Na, Sang Oh; Jeon, In Sang; Ahn, Hyo Seop; Park, Wan Suk; Lee, Suk Koo; Park, Kwi Won; Kim, Chong Jai; Chi, Je Geun

Original Article

Journal of the Korean Pediatric Society 1990;33(1):124-128.
Published online January 31, 1990.

A Case of Mucinous Cystadenocarcinoma in a Premenarchal Girl.

Hong Hoe Koo¹, Sang Oh Na¹, In Sang Jeon¹, Hyo Seop Ahn¹, Wan Suk Park², Suk Koo Lee², Kwi Won Park², Chong Jai Kim³, Je Geun Chi³

¹Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
²Department of Pediatric Surgery, College of Medicine, Seoul National University, Seoul, Korea
³Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea

초경전 소아에서의 난소의 점액성 낭선암종 1례

구홍희^¹^, 나상오^¹^, 전인상^¹^, 안효섭^¹^, 박완석^²^, 이석구^²^, 박귀원^²^, 김종재^³^, 지제근^³

^¹서울대학교 의과대학 소아과학교실
^²서울대학교 의과대학 소아외과학교실
^³서울대학교 의과대학 해부병리과학교실

Received: 3 September 1989 • Accepted: 3 September 1989

Abstract

In childhood, cancer of the ovary is highly unusual. It is responsible for only 1—2% of cancers found in patients under the age of 17. The frequency with which the various histologic types of ovarian neoplasm occur in childhood differs from that in adults. Epithelial tumors account for 70% to 80% of ovarian neoplasms in adults but only 20% in patients less than 20 years of age. The vast majority of ovarian epithelial tumors in childhood and adolescence are benign, so that a malignant ovarian epithelial neoplasm is extremely rare in the premenachal female. We have experienced a case of a mucinous cystadenocarcinoma in a premenarchal child. She had one-month history of vague abdominal discomfort and increasing abdominal girth. Physical examina- tion revealed a soft, smooth, mobile, fetal head-sized abdominopelvic mass. Abdominal ultrasonogra- phy showed an irregular thin walled huge pelvic mass with mixed echogenicity. At laparotomy, the patient had no ascites. A 23 x 15 x 13 cm smooth, cystic left adnexal mass was removed. The cut surface revealed solid and cystic portions filled with variable amount of chocolate colored fluid. A histologic diagnosis was mucinous cystadenocarcinoma. She was treated with unilateral salpingo- oophorectomy with subsequent survival and apparently normal menarche at 4 months after operation. She has no evidence of disease after 12 months of follow-up with chest P-A, abdominal ultrasonogrpa- hy and CA 125 value. A brief review of the literature was made.

Key Words: Ovarian Neoplasm, Cystadenocarcinoma, Premenarche