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Clinical Studies of Childhood Typhoid Fever during Outbreak.

Journal of the Korean Pediatric Society 1989;32(10):1345-1352.
Published online October 31, 1989.
Clinical Studies of Childhood Typhoid Fever during Outbreak.
Y M Choung, H K KIM, B T Kim, S C Park, Y C Kim, H J Cha, S J Lee
Department of Pediatrics, Soon Chun Hyang University Hospital, Seoul, Korea
1988 년 온천도시에서 유행한 소아기 장티프스의 임상적 고찰 - Widal 반응검사의 H-Titer를 중심으로 -
정용민, 김현국, 김병태, 박상철, 김영창, 차학주, 이상주
순천향대학 의학부 소아과학교실
Received: 14 March 1989   • Accepted: 30 May 1989
During 2 months from April 1988 to May 1988 when typhoid fever outbreak occured in the hot spring resort town, 52 cases of typhoid fever had been admitted to the department of Pediatrics Soon Chun Hyang Chun An Hospital, and evaluated clinically. The results were summarized as follows. 1) Among the 52 cases of typhoid fever, 28 were male and 24 were female. The peak age group was from 1 to 5 year of age and the youngest case was a 9 month old female patient. 2) The clinical findings during admission were as follows; fever (100%), poor appetite (80.8%), abdominal pain (75%), hepatomegaly (69.2%), throat injection (61.5%), abdominal tenderness (57.7%), diarrhea (55.8%), abdominal distension (53.8%), cough (46.2%), constipation (42.3%), splenomegaly (38. 5%), vomiting (38.5%), nausea (26.9%), and sore throat (17.3%). 3) The hematologic features on admission were as followes; anemia was 23.1%, leukopenia was revealed 26.9%, and thrombocytopenia was 26.7%. SGOT was elevated in 96%, and SGPT was elevated in 68%. In the bacteriologically proven cases, 0 agglutinin titer over 1:160 was 9.1%, and H agglutinin titer over 1:160 was 81.8%. The positive bacteriologic culture was 19.2% in blood, 46.2% in stool, and 19.2% both in blood and stool. 4) The average days of defervescence period was 3.76 days with ampicillin and Bactrim therapy. 5) Among the 52 cases, 7 cases developed complications, 5 case of bronchopneumonia, 1 case of GI hemorrhage, and hyponatremia respectively. The associated diseases were iron deficiency anemia, hepatitis carrier, and measles in 1 case respectively.
Key Words: Typhoid fever, Widal test

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