6 Cases of Intracranial Hemorrhage due to late Late Hemorrhage Disease of Infancy. |
Sang Ho Choi, Jae You Choi, Jee Sung Kim, Im Ju Kang |
Department of Pediatrics, Fatima Hospital, Dae Gu, Korea |
두개내 출혈을 동반한 영아기 출혈성 질환 6례 |
최상호, 최재유, 김지성, 강임주 |
대구 파티마병원 소아과 |
Received: 23 September 1987 |
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Abstract |
A bleeding syndrome in early infancy due to vitamin K deficiency has been reported sporadically
from various parts of world. The syndrome has similarities to hemorrhagic disease of newborn. The
main differences are that it is found in an older age group, the pathogenesis is unknown, and
intracranial hemorrhage are frequent with a resultant high mortality rate.
We have experienced 6 cases of spontaneous intracranial hemorrhage in the absence of known
trauma from 1 to 3 months of age.
Coagulation studies showed marked prolongation of prothrombin time and partial thromboplastin
time.
Satisfactory clinical and laboratory results were demonstrated after vitamin K administration and
fresh blood transfusion to correct the coagulation defect and anemia. |
Key Words:
Late hemorrhagic disease of infancy, Vitamin K deficiency, Intracranial hemorrhage |
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